LMNA, ID (LMNA, LMN1, Prelamin-A/C, Lamin-A/C, 70kD lamin, Renal carcinoma antigen NY-REN-32), 037834-200ul


LMNA, ID (LMNA, LMN1, Prelamin-A/C, Lamin-A/C, 70kD lamin, Renal carcinoma antigen NY-REN-32), 037834-200ul by United States Biological at Periodic Table on the Web. MPN: 037834. Hurry! Limited time offer. Offer valid only while supplies last. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encode


LMNA, ID (LMNA, LMN1, Prelamin-A/C, Lamin-A/C, 70kD lamin, Renal carcinoma antigen NY-REN-32), 037834-200ul by United States Biological
4.8 out of 5 stars with 17 reviews
Condition: New
Availability: In Stock
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Product Description & Reviews

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Features & Highlights

  • Pab
  • Human
  • Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
  • Purified by Protein A affinity chromatography.

Additional Information

Brand:
United States Biological
Manufacturer:
United States Biological
Category:
Antigens
MPN:
037834
Part Number:
037834
Publisher:
United States Biological
Item Weight:
0.01 pounds

 


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